Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

Blog Article

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor used in the remedy of a number of myeloma. Its synthesis or review is vital for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug used in the therapy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise forms of most cancers, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the generation process and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast cancer. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the remedy CAS NO. 134790-39-9 of colorectal cancer and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have several purposes, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, that are used in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication made use of to deal with form two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).